This is a very well designed and amazing art piece! I've rarely come across amazing artwork like this nowadays. Now, to the questions:
Vision: The vision is amazing! I really felt something when I looked at this, as if a sense of wanting to see them in real life. Like far away friends. The way you used the eye colors on the anthros is cool!
Originality: Wonderful Originality! The two posing for the picture really fits to the hidden message.
Technique: Excellent technique on making the picture seem real, while having some cartoon aspects in them. For a moment, I thought that this was an actual photo! The way the characters look is also amazing!
Impact: This Art piece really gives an impact to me and what it's message might be. Could this be a picture a friend sent to someone close to him? Or is it to his family? We may never know...
Overall: This amazing art piece really deserves to be a featured work on DA. You have an amazing gift and I encourage you to keep on going with amazing art work like this.